Search on: 5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE 
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Descriptor English:   5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase 
Descriptor Spanish:   5-Metiltetrahidrofolato-Homocisteína S-Metiltransferasa 
Descriptor Portuguese:   5-Metiltetra-Hidrofolato-Homocisteína S-Metiltransferase 
Synonyms English:   Methionine Synthetase
Methyltetrahydrofolate Homocysteine Methyltransferase
Tetrahydropteroylglutamate Methyltransferase  
Tree Number:   D08.811.913.555.500.645
Definition English:   An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobamide coenzyme. The enzyme can act on mono- or triglutamate derivatives. EC 2.1.1.13. 
Indexing Annotation English:   /defic: consider also HOMOCYSTINURIA; DF: note short X ref
See Related English:   Homocystinuria
 
History Note English:   98(75) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   14145 
Unique Identifier:   D013766 

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